Studies were conducted on 20 crossbred lambs of 4-5 months old. Ten la
mbs were Nali x, Corriedale cross (Hisardale) and the other 10 were Na
li x Lohi cross (Munjal). Seven lambs each of both crossbreeds were in
fected with 10,000 infective larvae of Haemonchus contortus. Three lam
bs of each crossbreed served as uninfected controls. Clinicopathologic
al examinations were done before and after infection and all the lambs
were necropsied 28 days post-infection. The body weight gain, haemogl
obin and packed cell volume were significantly lower in Hisardale lamb
s and the peripheral eosinophil count was significantly higher in Munj
al lambs. Significant hypoalbuminaemia and hypoglobulinaemia, a sharp
increase in albumin: globulin ratio; significantly higher faecal egg c
ounts; adult worm counts; abomasal pH, volume, congestion and oedema w
ere observed in Hisardale lambs as compared to Munjal lambs. Clinical
signs of haemonchosis were more severe in Hisardale lambs and two of t
hem died. Munjal lambs therefore seem less susceptible than Hisardale
lambs to H. contortus infection.