A NOVEL BIOMATERIAL - POLY(DIMETHYLSILOXANE)-POLYAMIDE MULTIBLOCK COPOLYMER .1. SYNTHESIS AND EVALUATION OF BLOOD COMPATIBILITY

Authors
FURUZONO T YASHIMA E KISHIDA A MARUYAMA I MATSUMOTO T AKASHI M
Citation
T. Furuzono et al., A NOVEL BIOMATERIAL - POLY(DIMETHYLSILOXANE)-POLYAMIDE MULTIBLOCK COPOLYMER .1. SYNTHESIS AND EVALUATION OF BLOOD COMPATIBILITY, Journal of biomaterials science. Polymer ed., 5(1-2), 1993, pp. 89-98
Citations number
24
Categorie Soggetti
Material Science","Engineering, Biomedical
Journal title
Journal of biomaterials science. Polymer ed. → ACNP
ISSN journal
09205063
Volume
5
Issue
1-2
Year of publication
1993
Pages
89 - 98
Database
ISI
SICI code
0920-5063(1993)5:1-2<89:ANB-PM>2.0.ZU;2-C
Abstract
Aramid-silicone resins (PASs) consisting of aromatic polyamide (aramid ) and poly(dimethylsiloxane) (PDMS) segments were synthesized by low t emperature solution polycondensation. For the evaluation of blood comp atibility in vitro, two kinds of experiments were carried out. One was the thromboxane B2(TXB2) release test from platelets attaching to PAS and Biomer(R). The other was the observation of the platelet adhesion on the surfaces of PAS by scanning electron microscopy (SEM). The res ults indicated that PAS was bio-inert in vitro. The surface chemical c omposition of PAS films was investigated by means of electron probe mi cro analysis (EPMA), X-ray photoelectron spectroscopy (XPS), and dynam ic contact angle measurements. The relationship between blood compatib ility and surface composition of PAS is discussed.