A SIMPLE G-BANDING TECHNIQUE ADAPTABLE FOR FLUORESCENT IN-SITU HYBRIDIZATION (FISH) AND PHYSICAL ORDERING OF HUMAN RENIN (REN) AND CATHEPSIN-E (CTSE) GENES BY MULTICOLOR FISH
J. Inazawa et al., A SIMPLE G-BANDING TECHNIQUE ADAPTABLE FOR FLUORESCENT IN-SITU HYBRIDIZATION (FISH) AND PHYSICAL ORDERING OF HUMAN RENIN (REN) AND CATHEPSIN-E (CTSE) GENES BY MULTICOLOR FISH, Acta histochemica et cytochemica, 26(4), 1993, pp. 319-324
We developed a simple technique for delineation of refined replication
G-band in combination with fluorescent in situ hybridization (FISH).
By using this system we localized three genes of pepsinogen C (PGC), r
enin (REN), and cathepsin E (CTSE) on 6p21.1, 1q32, and 1q32, respecti
vely. Further, we determined the physical order of REN and CTSE on chr
omosome band 1q32 as cen-(1q32)-REN-CTSE-tel by multi-color FISH.