IMMUNE-MEDIATED NEUROPATHIES

Identification of immune-mediated neuropathies is important as these d isorders often respond to treatment. Patterns of binding of serum M (m ononclonal) proteins and autoantibodies correlate with, and may be dia gnostic markers for, specific polyneuropathy syndromes. There is evide nce that some of these antibodies may play a pathogenic role in polyne uropathy syndromes. Identification of specific immune polyneuropathy s yndromes provides guidance regarding immunosuppressive regimens that m ay be effective treatments.