Cm. Philpot et D. Charles, DETERMINATION OF SENSITIVITY TO ANTIFUNGAL DRUGS - EVALUATION OF AN API KIT, British journal of biomedical science, 50(1), 1993, pp. 27-30
Evaluation of a commercial kit method for testing sensitivity of yeast
s to antifungal drugs was performed employing agar gel dilution as the
reference method. For the cidal drugs amphotericin B and flucytosine,
results were closely comparable. For the three azole drugs tested, mi
conazole, econazole and ketoconazole, the discrepant results obtained
probably relate to a number of factors affecting the end-point when te
sting these agents. Although easy to perform, the kit method is relati
vely expensive and the newer antifungal agents (e.g. fluconazole and i
traconazole) are not included. Though showing promise, the kit method
has limitations in its present format.