Evidence in human studies of the association of long term habitual exe
rcise with bone mineral content (BMC) and density (BMD) largely comes
from studies in athletes. In young adults, the highest BMC and BMD val
ues have been found in strength and power-trained athletes, while endu
rance activities such as long distance running and swimming seem less
effective with regard to peak bone density. Intensive endurance traini
ng may even be associated with amenorrhoea and decreased trabecular bo
ne density in young female. However, after menopause female athletes s
how greater bone mass indicating that they do not share the accelerate
d decline in BMC observed in a nonathletic population. Middle-aged and
elderly male athletes from various sports have significantly higher B
MC and BMD than controls, especially in trabecular bone sites, but hig
her cortical BMC has also been found in the dominant/nondominant arm c
omparisons with unilateral exercises such as tennis. The differences f
ound between female athletes and controls have generally been less pro
nounced that those among men, but a number of studies suggest in a wom
en long term physical training may counteract the low BMC and BMD asso
ciated with reduced bone mass. Although the interpretation of results
of cross-sectional studies should be treated with caution, studies in
athletes serve as an economical alternative approach to experimental t
rials with their long term follow-up and exercise compliance problems.
The difference found in BMD between those who have devoted themselves
to life-long training and those who have been much less active should
not be underestimated.