A nineteen month old male Hovawart dog was referred to the clinic with
a history of apathy and cryptococcosis was suspected. Clinical, radio
graphic and ultrasound examinations revealed lesions in various locati
ons of the skeletal system, the oral and nasal cavity in addition to r
etrobulbar and intraocular lesions. Cryptococcus neoformans was detect
ed microbially and histologically. Euthanasia was performed because of
the poor prognosis. Post mortem, further lesions were evident in the
central nervous system, the spleen, the lung and different lymph nodes
.