Rcm. Pan et al., HYPERTHYROIDISM FOLLOWED BY HYPERTHYROIDI SM DURING TREATMENT WITH AMIODARONE, Schweizerische medizinische Wochenschrift, 123(44), 1993, pp. 2110-2112
Hypothyroidism followed by hyperthyroidism is described in two patient
s treated by amiodarone. Euthyroidism was rapidly restored after treat
ment with antithyroid drugs and potassium perchlorate. The physiopatho
logy of amiodarone-induced hypothyroidism is discussed. Withdrawal of
amiodarone is advised in the case of both hypothyroidism and hyperthyr
oidism.