PARTICLE-SIZE AND THE CAKING TENDENCY OF A POWDER

Authors
PROVENT B CHULIA D CARY J
Citation
B. Provent et al., PARTICLE-SIZE AND THE CAKING TENDENCY OF A POWDER, European journal of pharmaceutics and biopharmaceutics, 39(5), 1993, pp. 202-207
Citations number
NO
Categorie Soggetti
Pharmacology & Pharmacy","Engineering, Chemical
Journal title
European journal of pharmaceutics and biopharmaceutics → ACNP
ISSN journal
09396411
Volume
39
Issue
5
Year of publication
1993
Pages
202 - 207
Database
ISI
SICI code
0939-6411(1993)39:5<202:PATCTO>2.0.ZU;2-L
Abstract
In this study, the main factors causing the phenomenon of caking of th e powder 11-amino-undecanoic acid were investigated. The most importan t cause identified was the size of the particles in the powder. A meth odological approach involving electron microscopy, sifting, Blaine per meametry and Jenike shear cell determination of flow is suggested for use in investigating the physical and rheological properties of powder s for the purpose of studying caking and in-process monitoring.