CEREBROVASCULAR COMPLICATIONS OF L-ASPARAGINASE THERAPY IN CHILDREN WITH LEUKEMIA - APHASIA AND OTHER NEUROPSYCHOLOGICAL DEFICITS

Authors
KINGMA A TAMMINGA RYJ KAMPS WA LECOULTRE R SAAN RJ
Citation
A. Kingma et al., CEREBROVASCULAR COMPLICATIONS OF L-ASPARAGINASE THERAPY IN CHILDREN WITH LEUKEMIA - APHASIA AND OTHER NEUROPSYCHOLOGICAL DEFICITS, Pediatric hematology and oncology, 10(4), 1993, pp. 303-309
Citations number
16
Categorie Soggetti
Pediatrics,Oncology,Hematology
Journal title
Pediatric hematology and oncology → ACNP
ISSN journal
08880018
Volume
10
Issue
4
Year of publication
1993
Pages
303 - 309
Database
ISI
SICI code
0888-0018(1993)10:4<303:CCOLTI>2.0.ZU;2-H
Abstract
Children with acute lymphoblastic leukemia (ALL), treated with L-aspar aginase are at risk for cerebral thrombosis or hemorrhage because of c oagulation protein deficiencies. The results and the importance of ser ial neuropsychological examination after such complications in three c hildren with ALL are presented. All patients showed marked aphasia and other cognitive deficits. Recovery was complete in two of three child ren.