M. Johannesson et al., THE COST OF SCREENING FOR HYPERCHOLESTEROLEMIA - RESULTS FROM A CLINICAL-TRIAL IN SWEDISH PRIMARY HEALTH-CARE, Scandinavian journal of clinical & laboratory investigation, 53(7), 1993, pp. 725-732
The cost of screening for hypercholesterolaemia in a clinical trial wa
s investigated at a primary health care centre. A convenience sample o
f the population was screened for inclusion in a study of the effectiv
eness of a lipid lowering programme. Included in the study were adults
30-59 years of age with a S-Cholesterol of 6.50-7.79 mmol l-1 at rand
omization, plus two previous values greater-than-or-equal-to 6.50 mmol
l-1 at screening and selection, with at least two other cardiovascula
r risk factors. In total 447 persons were screened and 37 were randomi
zed into the lipid lowering programme. The mean cost per randomized pe
rson was estimated at about SEK 7500 (Swedish Crowns). An analysis of
different inclusion criteria for treatment was also carried out. The c
ost of finding a patient to treat in the clinical trial was estimated
to be more than three times as high with a total cholesterol cut-off p
oint of 7.80 mmol l-1 compared with a cut-off point of 5.20 mmol l-1.