Optimisation in diagnostic radiology means achieving a reasonable comp
romise between high image quality and low dose to the patient. A conve
nient method to evaluate the influence of an examination technique on
patient dose is the calculation of organ doses using radiation transpo
rt codes together with computational human models. A brief history of
the computational models is given and the differences between mathemat
ical and tomographic models are described. Dose calculations performed
in nuclear medicine and diagnostic radiology are briefly summarised;
the limitations of calculated organ doses with respect to accuracy and
applicability to individual situations are discussed. Finally, the po
ssible use of dose calculations for optimisation procedures in diagnos
tic radiology, due to quantification of the effects of measures aimed
at dose reduction or limitation on single organ doses, is illustrated.