Jm. Chevallier et al., TOTAL COLECTOMY AND ILEORECTAL ANASTOMOSI S IN CROHNS COLITIS - FUNCTIONAL RESULTS AND RECURRENCE RATE (83 CASES), Gastroenterologie clinique et biologique, 17(10), 1993, pp. 723-732
Eighty-three consecutive patients (38 men, 45 women) underwent colecto
my and ileorectal anastomosis (IRA) for Crohn's colitis between 1960 a
nd 1988. The mean age at the time of IRA was 28.5 years after a mean i
nterval of four years from diagnosis. At the time of IRA, 31 patients
had proctitis, while 25 had perianal disease. Two patients died postop
eratively. Postoperative complications appeared in 21 cases (25.3 %) i
ncluding 7 anastomotic leaks (13.2 %). Leakage did not imply IRA compr
omise and the diverting ileostomy did not decrease the risk of preserv
ation of the ileorectal anastomosis. With a mean follow-up of 8 years
after IRA, among the 81 surviving patients, it was necessary to retain
the stomy in five, 24 required exclusion or excision of their IRA (10
defunctioning ileostomies, 14 proctectomies) and 52 still had a funct
ioning IRA at follow-up (64.2 %). Among the 43 recurrences (53 %), 21
underwent reoperation. The mean interval between IRA and recurrence wa
s 2.2 years. The cumulative rate of recurrence reached 47 % at 5 years
and 57 % at 10 years. Fifty percent of the patients still had a funct
ioning IRA and were satisfied. Preoperative ileal lesions affected the
functional results of the IRA and the recurrence rate. Development of
ileal rectal or anal disease after IRA significantly increased the ri
sk of exclusion of the rectum but did not require suppression of anal
function. Patients under 30 years of age or patients suffering for mor
e than 5 years had poorer functional results and more frequent reopera
tions at 5 years. Rectal preservation after IRA may be proposed with s
uccess to patients with a healthy rectum or with minimal or moderate p
roctitis, even if there is perianal disease that could be safely treat
ed before IRA. In this last setting, the patient has to be informed of
the risk of rectal preservation and the possible risk of requiring ul
terior proctectomy.