E. Proano et L. Perbeck, CHANGES IN SKIN BLOOD-FLOW IN ISCHEMIC LIMBS AFTER VASCULAR RECONSTRUCTION MEASURED BY FLUORESCEIN FLOWMETRY AND LASER-DOPPLER FLOWMETRY, Clinical physiology, 13(6), 1993, pp. 599-609
It is not known to what extent the skin blood flow increases after vas
cular reconstruction in ischaemic limbs. Thus, a study was undertaken
to measure skin blood flow, using the two techniques laser Doppler flo
wmetry and fluorescein flowmetry, before and after vascular reconstruc
tion. The skin temperature was measured also. The plantar circulation
was assessed in 14 patients (9 non-diabetics and 5 diabetics; mean age
65 years; range 47-80), with the patient in the supine position, 1-2
days before and 8-10 days after surgery. After vascular reconstruction
the skin blood flow increased by 240% (P < 0.01) when measured by flu
orescein flowmetry and by 148% (P < 0.01) when measured by laser Doppl
er flowmetry, and the skin temperature rose by 3.2-degrees-C (P < 0.1)
. In the contralateral non-operated limb there was no significant chan
ge in skin blood flow as measured by the two methods. The results impl
y that after vascular reconstruction in ischaemic limbs the skin blood
flow increases both in the superficial layer as determined by fluores
cein flowmetry (which measures the blood flow down to 0.6 mm) and in d
eeper layers as determined by laser Doppler flowmetry (which measures
flux down to 6 mm).