CHANGES IN SKIN BLOOD-FLOW IN ISCHEMIC LIMBS AFTER VASCULAR RECONSTRUCTION MEASURED BY FLUORESCEIN FLOWMETRY AND LASER-DOPPLER FLOWMETRY

Citation
E. Proano et L. Perbeck, CHANGES IN SKIN BLOOD-FLOW IN ISCHEMIC LIMBS AFTER VASCULAR RECONSTRUCTION MEASURED BY FLUORESCEIN FLOWMETRY AND LASER-DOPPLER FLOWMETRY, Clinical physiology, 13(6), 1993, pp. 599-609
Citations number
15
Categorie Soggetti
Physiology
Journal title
ISSN journal
01445979
Volume
13
Issue
6
Year of publication
1993
Pages
599 - 609
Database
ISI
SICI code
0144-5979(1993)13:6<599:CISBII>2.0.ZU;2-R
Abstract
It is not known to what extent the skin blood flow increases after vas cular reconstruction in ischaemic limbs. Thus, a study was undertaken to measure skin blood flow, using the two techniques laser Doppler flo wmetry and fluorescein flowmetry, before and after vascular reconstruc tion. The skin temperature was measured also. The plantar circulation was assessed in 14 patients (9 non-diabetics and 5 diabetics; mean age 65 years; range 47-80), with the patient in the supine position, 1-2 days before and 8-10 days after surgery. After vascular reconstruction the skin blood flow increased by 240% (P < 0.01) when measured by flu orescein flowmetry and by 148% (P < 0.01) when measured by laser Doppl er flowmetry, and the skin temperature rose by 3.2-degrees-C (P < 0.1) . In the contralateral non-operated limb there was no significant chan ge in skin blood flow as measured by the two methods. The results impl y that after vascular reconstruction in ischaemic limbs the skin blood flow increases both in the superficial layer as determined by fluores cein flowmetry (which measures the blood flow down to 0.6 mm) and in d eeper layers as determined by laser Doppler flowmetry (which measures flux down to 6 mm).