[NI2(OAC)3(UREA)(TMEN)2](OTF) AND [NI(OAC)(UREA)2(TMEN)](OTF), MODEL COMPLEXES FOR THE ENZYME UREASE

Authors
WAGES HE TAFT KL LIPPARD SJ
Citation
He. Wages et al., [NI2(OAC)3(UREA)(TMEN)2](OTF) AND [NI(OAC)(UREA)2(TMEN)](OTF), MODEL COMPLEXES FOR THE ENZYME UREASE, Inorganic chemistry, 32(23), 1993, pp. 4985-4987
Citations number
47
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Inorganic chemistry → ACNP
ISSN journal
00201669
Volume
32
Issue
23
Year of publication
1993
Pages
4985 - 4987
Database
ISI
SICI code
0020-1669(1993)32:23<4985:[A[MC>2.0.ZU;2-8
Abstract
Dinuclear and mononuclear Ni(II) complexes [Ni2(OAc)3(urea)(tmen)2](OT f) and [Ni(OAc)(urea)2(tmen)](OTf) were prepared from the reaction of [Ni2(OH2)(OAC)4(tmen)2] with Me3Si(OTf) and urea. The two complexes re produce several of the known structural and spectroscopic properties o f the dinickel core in the enzyme urease, which catalyzes the hydrolys is of urea into ammonium and carbamate. The dinuclear complex, in part icular, having two nickel ions and a single coordinated urea molecule, assembles several components of the substrate-bound form of the enzym e.