L. Ostergaard et Pl. Andersen, ETIOLOGY OF COMMUNITY-ACQUIRED PNEUMONIA - EVALUATION BY TRANSTRACHEAL ASPIRATION, BLOOD CULTURE, OR SEROLOGY, Chest, 104(5), 1993, pp. 1400-1407
In a 5-year period, 254 patients with community-acquired pneumonia wer
e attended to. Transtracheal aspiration (TTA) could be performed on 11
9 patients, blood cultures were performed on 201 patients, and 74 pati
ents underwent serologic examinations. By use of these procedures, an
etiologic diagnosis was established in 93 cases. Streptococcus pneumon
iae was the most common pathogen as it was found in 35 cases. Eleven o
f these 35 patients (31.4 percent) had pneumococcemia, and the mortali
ty in this group was 27.3 percent. None of the patients with pneumococ
cal pneumonia and negative blood culture died. Haemophilus influenzae
was the only isolated pathogen from transtracheal aspirated sputum in
16 cases and accounted for 17.5 percent of pneumonias in previous heal
thy individuals under 50 years of age. Mycoplasma pneumonia infections
, Legionella pneumophila infections, and Chlamydia infections were fou
nd in ten, eight, and three cases, respectively. The overall agreement
between microscopy and culture of respiratory secretions obtained by
TTA was 58.8 percent, and microscopy can be a guide when choosing the
initial antibiotic treatment. No statistically significant difference
in the rate of isolating bacteria among patients treated with antibiot
ics prior to TTA and patients not previously treated with antibiotics
was seen. When contraindications were respected, we found TTA to be a
safe procedure.