Physiological immaturity of the respiratory musculature and central re
spiratory control centres leads to an increased risk of apnoea and res
piratory complications following general anaesthesia in neonates. Regi
onal anaesthetic techniques may obviate the need for general anaesthes
ia and lessen the risks of perioperative morbidity. Although these tec
hniques have been described in infants, previous reports have dealt wi
th single shot techniques for brief surgical procedures (<60 min) Expe
rience with prolonged operative cases using regional anaesthesia via i
ndwelling catheters in infants is limited We present our experience wi
th four infants in whom either caudal epidural or spinal anaesthesia w
as administered via indwelling catheters for operative procedures that
lasted 90 to 180 min. We believe this technique is an alternative to
general anaesthesia in these patients.