Dw. Chakeres et al., MR OF HEAD AND NECK ADENOPATHY IN ASYMPTOMATIC HIV-SEROPOSITIVE MEN, American journal of neuroradiology, 14(6), 1993, pp. 1367-1371
Citations number
17
Categorie Soggetti
Neurosciences,"Radiology,Nuclear Medicine & Medical Imaging
PURPOSE: Adenopathy is a well-known component of AIDS-related complex.
Our goal was to determine whether asymptomatic HIV-infected persons h
ave characteristic findings of head and neck adenopathy on MR imaging
and whether there is an association between the MR findings and the CD
4 lymphocyte counts. METHODS: We blindly and retrospectively evaluated
the distribution and size of lymphadenopathy seen on screening MR exa
minations that were performed on 50 asymptomatic HIV-positive male sub
jects and 50 age-matched HIV-negative control subjects. We also correl
ated the imaging findings in HIV-seropositive and -seronegative subjec
ts with their CD4 counts. RESULTS: The HIV-positive subjects had a hig
her incidence of adenopathy compared with the controls. Statistically
significant differences were found between the groups in size and numb
er of neck lymph nodes, thickness of the adenoids, size of high, deep
cervical-retropharyngeal lymph nodes, and presence of parotid abnormal
ities. We found a correlation between increasing lymph node size and d
ecreasing CD4 levels. CONCLUSION: We conclude that HIV-positive asympt
omatic patients have a high incidence of head and neck abnormalities i
ncluding lymphadenopathy, and alteration in their CD4 counts not commo
nly seen in seronegative control subjects.