STUDIES ON THE METALATION AND ALKYLATION OF DIHYDROTHIEPIN-1,1-DIOXIDE - APPLICATIONS TO SYNTHESIS

Authors
RIGBY JH KRUEGER AC
Citation
Jh. Rigby et Ac. Krueger, STUDIES ON THE METALATION AND ALKYLATION OF DIHYDROTHIEPIN-1,1-DIOXIDE - APPLICATIONS TO SYNTHESIS, Synlett, (11), 1993, pp. 829-830
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
11
Year of publication
1993
Pages
829 - 830
Database
ISI
SICI code
0936-5214(1993):11<829:SOTMAA>2.0.ZU;2-9
Abstract
Alpha-Lithiodihydrothiepin-1,1-dioxide is prepared by treatment of the parent heterocycle with n-BuLi. Alkylation of this species with a wid e range of electrophiles has been achieved. Subsequent thermal extrusi on of sulfur dioxide affords the corresponding terminally alkylated he xatrienes.