CHARACTERIZATION OF A UNIQUE RETROVIRAL RECOMBINANT CONTAINING 7S-L SEQUENCES

Authors
HAJJAR AM LINIAL ML
Citation
Am. Hajjar et Ml. Linial, CHARACTERIZATION OF A UNIQUE RETROVIRAL RECOMBINANT CONTAINING 7S-L SEQUENCES, Journal of virology, 67(12), 1993, pp. 7677-7679
Citations number
7
Categorie Soggetti
Virology
Journal title
Journal of virology → ACNP
ISSN journal
0022538X
Volume
67
Issue
12
Year of publication
1993
Pages
7677 - 7679
Database
ISI
SICI code
0022-538X(1993)67:12<7677:COAURR>2.0.ZU;2-#
Abstract
Using a recently described system to generate recombinants between avi an leukosis viruses (ALV) and cellular neo mRNA (A. M. Hajjar and M. L . Linial, J. Virol. 67:3845-3853, 1993), we isolated a recombinant con taining 7S L sequences. Analysis of this recombinant revealed that it most likely arose during reverse transcription of three copackaged RNA s: 7S L RNA, neo RNA, and ALV genomic RNA. Reverse transcription appea rs to have initiated on the 7S L RNA. A model for the generation of th is recombinant is described.