PLATELETS IN ESSENTIAL-HYPERTENSION

Authors
NITYANAND S PANDE I BAJPAI VK SINGH L CHANDRA M SINGH BN
Citation
S. Nityanand et al., PLATELETS IN ESSENTIAL-HYPERTENSION, Thrombosis research, 72(5), 1993, pp. 447-454
Citations number
22
Categorie Soggetti
Hematology,"Cardiac & Cardiovascular System
Journal title
Thrombosis research → ACNP
ISSN journal
00493848
Volume
72
Issue
5
Year of publication
1993
Pages
447 - 454
Database
ISI
SICI code
0049-3848(1993)72:5<447:PIE>2.0.ZU;2-2
Abstract
The ultrastructure and adenosine diphosphate induced aggregatory respo nse of platelets of 39 patients with essential hypertension have been studied. Both, transmission and scanning electron microscopy showed th e co-existence of various morphological forms of platelets suggestive of activation. The hypertensive platelets also exhibited increased sen sitivity to ADP induced aggregation confirming the activated state of platelets; the degree of activation correlated well with the levels of diastolic blood pressure.