In human kidney transplantation hypertension and renal dysfunction are
common complications. Diagnosis of vascular involvement may frequentl
y be necessary. Although iliac artery stenosis is a rare complication
after renal transplantation, it can be the cause of hypertension and r
enal dysfunction. Because colour duplex scanning is a repeatable non-i
nvasive technique, it may provide a useful tool in establishing a diag
nosis of iliac artery stenosis in patients with hypertension and/or re
nal dysfunction. We present four cases of iliac artery stenosis in kid
ney allograft recipients. Colour duplex scanning was used in these pat
ients to detect and localize the stenosis. Quantitative analysis of Do
ppler spectra was used to compare the Doppler spectrum waveforms obtai
ned from both femoral arteries and from the kidney allograft arteries
of these patients with the normal range. This normal range was determi
ned from Doppler spectra obtained in a control group of 21 kidney allo
graft recipients. Clinical data, arterial DSA, and the outcome of trea
tment were used to validate colour duplex findings in the patients wit
h iliac artery stenosis. Quantitative analysis of Doppler spectra show
ed differences between the femoral artery on the affected side and the
contralateral side outside the normal range. In three patients the il
iac artery stenosis was located proximal from the anastomosis with the
kidney allograft artery and in these three patients Doppler parameter
s obtained from the allograft artery were also outside the normal rang
e. In one patient the stenosis was located distally from the anastomos
is with the kidney allograft artery. In this case Doppler spectra from
the kidney allograft artery were within the normal range. In two pati
ents the clinical course neccessitated correction of the stenosis. Ren
al function and Doppler spectra from the arteries normalized after cor
rection. In conclusion, comprehensive use of colour duplex scanning wi
th quantitative analysis of Doppler spectra enables accurate non-invas
ive diagnosis and localization of iliac artery stenoses in kidney allo
graft recipients and facilitates selection of the appropriate clinical
approach.