THE EFFECT OF LONG-CHAIN N-ACYLETHANOLAMINES ON SOME MEMBRANE-ASSOCIATED FUNCTIONS OF NEUROBLASTOMA C1300-N18 CELLS

Authors
GULAYA NM MELNIK AA BALKOV DI VOLKOV GL VYSOTSKIY MV VASKOVSKY VE
Citation
Nm. Gulaya et al., THE EFFECT OF LONG-CHAIN N-ACYLETHANOLAMINES ON SOME MEMBRANE-ASSOCIATED FUNCTIONS OF NEUROBLASTOMA C1300-N18 CELLS, Biochimica et biophysica acta, 1152(2), 1993, pp. 280-288
Citations number
34
Categorie Soggetti
Biophysics,Biology
Journal title
Biochimica et biophysica acta → ACNP
ISSN journal
00063002
Volume
1152
Issue
2
Year of publication
1993
Pages
280 - 288
Database
ISI
SICI code
0006-3002(1993)1152:2<280:TEOLNO>2.0.ZU;2-L
Abstract
As reported earlier (Gulaya, N.M., Vaskovsky, V.E., Vysotsky, M.V., Vo lkov, G.L., Govseeva, N.N. and Artemenko, I.P. (1988) Ukr. Biochim. J. 60, 58-63), N-acylphosphatidylethanolamines (NAPE) and products of th eir catabolism, N-acylethanolamines (NAE), are present in the lipids o f neuroblastoma C1300 N18 undifferentiated cells. The present paper de scribes the distribution of NAE added to culture medium of differentia ted cells and its effect on the fast sodium channels and some other me mbrane characteristics. It is shown that NAE inhibits the destroying a ction of veratridine on membranes.