CLINICAL, ELECTROENCEPHALOGRAPHIC AND RAD IOLOGICAL FEATURES OF LISSENCEPHALY - 2 CASES

Authors
GIROUD M FRANCOIS C DURAND C COUAILLIER JF BAUDOIN N DUMAS R NIVELON JL
Citation
M. Giroud et al., CLINICAL, ELECTROENCEPHALOGRAPHIC AND RAD IOLOGICAL FEATURES OF LISSENCEPHALY - 2 CASES, Revue neurologique, 149(10), 1993, pp. 536-540
Citations number
19
Categorie Soggetti
Clinical Neurology
Journal title
Revue neurologique → ACNP
ISSN journal
00353787
Volume
149
Issue
10
Year of publication
1993
Pages
536 - 540
Database
ISI
SICI code
0035-3787(1993)149:10<536:CEARIF>2.0.ZU;2-K
Abstract
We report 2 cases of lissencephaly and review the cardinal symptoms : microcephalia, mental retardation, pyramidal syndrome and generalized epilepsy. CT-Scan and MRI show the anatomical abnormalities of this ma lformation : microcephalia, smooth cortex reducing the surface of whit e matter and lack of sulci and gyri. The fact that the myelin is norma l on MRI suggests that this major disorder of neuronal migration does not come from radial glial fibers.