Between 1986 and 1988 the annual incidence of invasive melanoma in the
Hunter area of New South Wales, Australia, almost doubled to 52.5 per
100,000 in men and 42.9 per 100,000 in women. These rates have been m
aintained and are similar to those reported for 1987 in Queensland, Au
stralia, which are the highest in the world. Most of the increase in i
ncidence was in melanomas less than 1.50 mm in thickness, and adults o
f both sexes and all ages were affected. Thicker melanomas also increa
sed in incidence but only in adults 45 years and older, and mainly in
men. An analysis of health insurance data on treatment of skin lesions
and data from a histopathology laboratory suggested that diagnosis an
d treatment of skin lesions generally in the Hunter area had increased
almost 2-fold over this period. Advancement of the time of diagnosis
and a real increase in incidence were likely explanations for some of
the observed trends. Increasing diagnosis of a non-metastasising form
of thin melanoma, consequent upon increasing removal of pigmented skin
lesions by medical practitioners, may also explain some of the observ
ed increase in the incidence of the disease. This possibility has impo
rtant implications for proposed population screening programs, and met
hods are needed to distinguish such lesions, if they exist, from poten
tially fatal melanoma. (C) 1993 Wiley-Liss, Inc.