INTRAVESICAL INSTILLATION OF OXYBUTYNIN HYDROCHLORIDE FOR DETRUSOR HYPER-REFLEXIA

The effect of intravesical oxybutynin hydrochloride on detrusor behavi our was studied in 15 patients with urinary incontinence due to detrus or hyper-reflexia by ambulatory bladder monitoring. Twelve patients ha d a reduction in the frequency and amplitude of hyper-reflexic contrac tions and incontinence episodes following oxybutynin administration. I ntravesical oxybutynin may have a role in the management of patients o n intermittent self-catheterisation with detrusor hyper-reflexia who c annot tolerate the side effects of anticholinergic agents, including o xybutynin.