K. Yoshino et al., PLASMA ANDROGENS AND SEX-HORMONE BINDING GLOBULIN IN WOMEN WITH POLYCYSTIC OVARIES DIAGNOSED BY TRANSVAGINAL ULTRASOUND, Journal of reproductive medicine, 38(11), 1993, pp. 858-862
In order to investigate the androgen and sex hormone binding globulin
(SHBG) levels in the polycystic ovary, we compared the total testoster
one, free testosterone and SHBG levels in three patterns of polycystic
ovary diagnosed with transvaginal ultrasonography (18 in group 1, few
er than 5 cysts identified; 16 in group 2, 5-10 cysts; and 27 in group
3, 10 or more). Free testosterone, but not total testosterone, signif
icantly correlated with body mass index. Androgen levels were found to
increase and SHBG levels to decrease with increases in the amount of
ovarian cysts, and the evaluation of free testosterone was important i
n diagnosing the polycystic ovary syndrome.