CANINE-DISTEMPER VIRUS-REPLICATION IN CELLS ON MICROCARRIERS

Authors
LESKO J VEBER P DUSEKOVA E
Citation
J. Lesko et al., CANINE-DISTEMPER VIRUS-REPLICATION IN CELLS ON MICROCARRIERS, Acta virologica, 37(5), 1993, pp. 412-416
Citations number
12
Categorie Soggetti
Virology
Journal title
Acta virologica → ACNP
ISSN journal
0001723X
Volume
37
Issue
5
Year of publication
1993
Pages
412 - 416
Database
ISI
SICI code
0001-723X(1993)37:5<412:CVICOM>2.0.ZU;2-5
Abstract
Chick embryo and Vero cells were grown on Gelaspher M gelatin microcar riers in suspension culture. The microcarriers had no adverse effects on cell morphology and growth. Microcarrier cell cultures were used fo r large-scale production of canine distemper virus. Virus yields (TCID 50 per ml) were more than 10-times higher as compared to stationary ce ll culture.