Two cases of polyarthritis in the dog resulting from Leishmania specie
s infection are reviewed. The clinical investigations, laboratory find
ings and serological tests are summarised. Leishmanial amastigotes wer
e detected in synovial fluid samples of multiple joints with marked in
flammatory signs. Diagnosis was made by biopsy of bone marrow, skin an
d synovial fluid. Both dogs were initially treated with pentavalent so
dium stibogluconate. Other causes of canine polyarthritis were exclude
d.