TRANSFORMATION OF ALPHA-SANTONIN VIA 2 INDEPENDENT PATHWAYS BY PSEUDOMONAS STRAIN-S ATCC-43388

Authors
COLACO D FURTADO I NAIK UP MAVINKURVE S PAKNIKAR SK
Citation
D. Colaco et al., TRANSFORMATION OF ALPHA-SANTONIN VIA 2 INDEPENDENT PATHWAYS BY PSEUDOMONAS STRAIN-S ATCC-43388, Letters in applied microbiology, 17(5), 1993, pp. 212-214
Citations number
13
Categorie Soggetti
Microbiology,"Biothechnology & Applied Migrobiology
Journal title
Letters in applied microbiology → ACNP
ISSN journal
02668254
Volume
17
Issue
5
Year of publication
1993
Pages
212 - 214
Database
ISI
SICI code
0266-8254(1993)17:5<212:TOAV2I>2.0.ZU;2-W
Abstract
Pseudomonas strain S (ATCC 43388) transforms alpha-santonin in the pre sence of dicyclohexylcarbodiimide (DCCD) to 1,2-dihydrosantonin (DHS) and two more products, D1 and D2. D2 was identified as 4,5-dihydroxysa ntonin (DHXS). Cells incubated with semicarbazide (SC) formed DHXS but not DHS. Simultaneous formation of DHS and DHXS is indicative of the presence of two distinct pathways of alpha-santonin biotransformation.