SYNTHESIS AND SQUALENE SYNTHETASE INHIBITORY ACTIVITY OF TRIPOTASSIUM-N-FARNESYL)AMINOETHYLPHOSPHINATO]ETHYLPHOSPHONATE AS A TETHERED ANALOG OF N-BENZYL-N-FARNESYLAMINE-INORGANIC PYROPHOSPHATE ION-PAIR

Authors
PRASHAD M
Citation
M. Prashad, SYNTHESIS AND SQUALENE SYNTHETASE INHIBITORY ACTIVITY OF TRIPOTASSIUM-N-FARNESYL)AMINOETHYLPHOSPHINATO]ETHYLPHOSPHONATE AS A TETHERED ANALOG OF N-BENZYL-N-FARNESYLAMINE-INORGANIC PYROPHOSPHATE ION-PAIR, Bioorganic & medicinal chemistry letters, 3(10), 1993, pp. 2051-2054
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
3
Issue
10
Year of publication
1993
Pages
2051 - 2054
Database
ISI
SICI code
0960-894X(1993)3:10<2051:SASSIA>2.0.ZU;2-L
Abstract
Synthesis and squalene synthetase inhibitory activity of tripotassium -N-farnesyl)aminoethylphosphinato]ethylphosphonate (2) as a tethered a nalog of N-benzyl-N-farnesylamine(1)-PPi ion pair, using phosphinato(d imethylmethyl)phosphonate as a PPi mimic, is described.