THE EFFECT OF HEMODIALYSIS UPON SERUM LEVELS OF FLUORIDE

Serum and dialysate ionic fluoride (F-) were determined in 29 patients under hemodialysis (HD) treatment. Serum creatinine (Cr), blood urea nitrogen (BUN) and phosphorus (P) were also examined before and after HD in 92 patients including the above 29 patients under the same treat ment. Results reveal that serum F- levels of the patients before and a fter HD were statistically higher than those of the healthy subjects. The dialysis clearance of F- was 55.6 +/- 101.3 ml/min and the value w as statistically significantly lower than those of Cr, BUN (95%, p < 0 .001) and P (95%, p < 0.01). Based on these results, it is concluded t hat despite a net clearance of F- during a given HD procedure, serum F - failed to return to normal.