To assess the use of drainage implants in pediatric patients with glau
coma refractory to conventional medical and surgical therapy, we retro
spectively reviewed 20 consecutive eyes in children 10 years of age or
younger treated with 16 Molteno (three of which were removed and repl
aced with second Molteno shunts) and seven Baerveldt implants. The age
of the patients ranged from 1 month to 10 years (mean, 3 years). The
patients had undergone a mean of two previous failed glaucoma procedur
es (range, one to six). The mean intraocular pressure (IOP) prior to d
rainage tube implantation was 37 +/- 4 mm Hg, compared with a mean of
18 +/- 6 mm Hg following surgery, with average postoperative follow up
of 25 months (range, 8 to 41 months). The overall success, defined as
IOP less-than-or-equal-to 21 mm Hg without further surgical therapy,
was 80%. Postoperative glaucoma medications were required in 75% of pa
tients. There were 23 complications, one of which resulted in decrease
d visual acuity. These findings demonstrate that drainage tube implant
s can be effective in lowering IOP in uncontrolled pediatric glaucomas
. Patients often require postoperative glaucoma medications and close
monitoring for complications.