Objective: To examine the patterns of tests requested for patients adm
itted with chest pain, and to monitor the effects on those patterns of
issuing a set of guidelines formulated by an expert panel. Setting: T
ertiary referral hospital (teaching). Design: A retrospective audit of
the patterns of testing of patients with chest pain compared with tes
ting recommended by an expert panel, followed by comparison with patte
rns of testing after guidelines were issued. Intervention: Practice gu
idelines, based on the expert committee's recommendations, were drawn
up for use in the cardiology unit. Outcome measures: Tests per admissi
on, bed days per admission, emergency readmission rate. Patients: Sixt
y-seven patients with diagnosis at the time of admission of chest pain
and a discharge diagnosis of ''Intermediate coronary syndrome''. Resu
lts: The major finding of the audit was the excessive use of ''biochem
istry test profiles'' instead of targeted tests as recommended by the
expert committee. Intervention led to a decrease in the number of test
s per admission in the cardiology unit from an average of 22.9 tests i
n the six months before intervention to 9.7 in the six months after (P
< 0.001). There was no effect on bed days per admission or emergency
readmission rates. Conclusion: Audit and intervention in a specialised
unit of patients with a specified diagnosis led to more cost effectiv
e use of the resources of the Royal Melbourne Hospital Department of B
iochemistry.