MOLECULAR-STRUCTURES OF 4 TRITERPENOIDS - X-RAY CRYSTALLOGRAPHIC ANALYSIS OF METHYL -TRIACETOXY-19-ALPHA-HYDROXYURS-12-EN-28-BETA-OATE

Authors
COX PJ DURHAM DG LIU XJ RICHARDS RME
Citation
Pj. Cox et al., MOLECULAR-STRUCTURES OF 4 TRITERPENOIDS - X-RAY CRYSTALLOGRAPHIC ANALYSIS OF METHYL -TRIACETOXY-19-ALPHA-HYDROXYURS-12-EN-28-BETA-OATE, Journal of crystallographic and spectroscopic research, 23(10), 1993, pp. 779-783
Citations number
11
Categorie Soggetti
Crystallography,Spectroscopy
Journal title
Journal of crystallographic and spectroscopic research → ACNP
ISSN journal
02778068
Volume
23
Issue
10
Year of publication
1993
Pages
779 - 783
Database
ISI
SICI code
0277-8068(1993)23:10<779:MO4T-X>2.0.ZU;2-S
Abstract
A triterpenoid glycoside has been isolated from the roots of a herb us ed in traditional Chinese medicine. The molecular structure of this co mpound and its derivatives have been determined by spectroscopic studi es and an X-ray analysis of the 2alpha,3beta,23alpha-triacetoxy-28beta -methyl ester of the aglycone. This aglycone belongs to the ursene str ucture series. The hydroxy group on ring E of these triterpenoids is a lpha orientated and the side chains at C(2), C(3), C(4) and C(17) are alpha, beta, alpha and beta orientated, respectively. The C ring, whic h has a double bond at C(12)=C(13), adopts a sofa conformation.