LIPOSOMAL AMPHOTERICIN-B TREATMENT OF ASPERGILLOSIS IN A RENAL-TRANSPLANT PATIENT

Authors
ELLIS ME BOHLEGA S HALIM MA QUNIBI W THARPE W
Citation
Me. Ellis et al., LIPOSOMAL AMPHOTERICIN-B TREATMENT OF ASPERGILLOSIS IN A RENAL-TRANSPLANT PATIENT, Saudi medical journal, 14(5), 1993, pp. 469-470
Citations number
NO
Categorie Soggetti
Medicine, General & Internal
Journal title
Saudi medical journal → ACNP
ISSN journal
03795284
Volume
14
Issue
5
Year of publication
1993
Pages
469 - 470
Database
ISI
SICI code
0379-5284(1993)14:5<469:LATOAI>2.0.ZU;2-5
Abstract
A renal transplant recipient developed intracranial aspergillosis, and whilst receiving conventional amphotericin B therapy (1 mg/kg daily) developed acute anuric renal failure necessitating discontinuation of therapy. He then received liposomal amphotericin B (Ambisome(R)) at 2 mg/kg daily with no recurrence of renal toxicity. Liposomal amphoteric in B appears to be safe in the management of severe fungal infections in renal transplant patients in whom preservation of renal function is crucial.