SYNTHESIS OF POTENTIAL NAFTOPIDIL METABOL ITES

Authors
KUTSCHER B ENGEL J FLEISCHHAUER I NIEBCH G
Citation
B. Kutscher et al., SYNTHESIS OF POTENTIAL NAFTOPIDIL METABOL ITES, Archiv der pharmazie, 326(10), 1993, pp. 803-806
Citations number
6
Categorie Soggetti
Chemistry,"Pharmacology & Pharmacy
Journal title
Archiv der pharmazie → ACNP
ISSN journal
03656233
Volume
326
Issue
10
Year of publication
1993
Pages
803 - 806
Database
ISI
SICI code
0365-6233(1993)326:10<803:SOPNMI>2.0.ZU;2-C
Abstract
The synthesis of four proposed metabolites 14 of Naftopidil, a selecti ve alpha1-antagonist, is reported. These compounds comprise hydroxylat ed and demethylated derivatives and a cleavage product of Naftopidil.