DIFFERENTIATION OF UNITED-STATES AND EUROPEAN ISOLATES OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS BY MONOCLONAL-ANTIBODIES

Authors
NELSON EA CHRISTOPHERHENNINGS J DREW T WENSVOORT G COLLINS JE BENFIELD DA
Citation
Ea. Nelson et al., DIFFERENTIATION OF UNITED-STATES AND EUROPEAN ISOLATES OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS BY MONOCLONAL-ANTIBODIES, Journal of clinical microbiology, 31(12), 1993, pp. 3184-3189
Citations number
25
Categorie Soggetti
Microbiology
Journal title
Journal of clinical microbiology → ACNP
ISSN journal
00951137
Volume
31
Issue
12
Year of publication
1993
Pages
3184 - 3189
Database
ISI
SICI code
0095-1137(1993)31:12<3184:DOUAEI>2.0.ZU;2-1
Abstract
Monoclonal antibodies (MAbs) to two U.S. isolates of porcine reproduct ive and respiratory syndrome (PRRS) virus were prepared. Two MAbs spec ifically recognized a conserved epitope on the putative 15-kDa nucleoc apsid protein of U.S. and European isolates of PRRS virus. Four other MAbs recognized epitopes on the 15-kDa protein of U.S. but not Europea n isolates of PRRS virus. Collectively, this indicates that PRRS virus es contain both conserved and divergent epitopes on the 15-kDa viral p rotein.