Objective The goal of this study was to prospectively define the impac
t of laparoscopy on the management of patients with a presumed diagnos
is of appendicitis. Summary Background Data While the role of laparosc
opy in the management of cholelithiasis is well established, its impac
t on the management of acute appendicitis needs to be objectively defi
ned and compared to that of conventional management. Several authors h
ave predicted that laparoscopic appendectomy will become the preferred
treatment for appendicitis. Methods Two groups of consecutive patient
s with similar clinical characteristics of acute appendicitis were com
pared. Data on the laparoscopic group were compiled prospectively on s
tandardized forms; data on the conventional group were collected retro
spectively. Operative time, hospital stay, analgesia, cost, and return
to normal activities were noted. Results Seventeen consecutive patien
ts who underwent appendectomy were compared to 18 consecutive patients
who underwent laparoscopy (16 of these 18 had laparoscopic appendecto
my). There was no significant difference between the two groups in ter
ms of clinical characteristics and appendiceal histopathology. The mea
n operative times were 61 +/- 4.1 minutes and 46 +/- 2.9 minutes for t
he laparoscopy and conventional groups, respectively (p < 0.01). Hospi
tal stay was significantly shorter in the laparoscopic appendectomy gr
oup, with 81% of patients being discharged on their first postoperativ
e day (p < 0.001). The laparoscopic appendectomy patients required sig
nificantly less narcotic analgesia (p < 0.02). Return to normal activi
ty was not significantly different between the two groups. The average
total cost of laparoscopic appendectomy was 30% greater than that of
conventional appendectomy. Conclusions Laparoscopy is a useful adjunct
to the management of patients with a presumed clinical diagnosis of a
cute appendicitis.