This study examines how the convulsive threshold in electroconvulsive
therapy (ECT) varies with electrode placement (bilateral [BL] versus r
ight unilateral [RUL]), age, gender, weight, and the nasion-inion meas
urements of the head. Method: Twenty-eight subjects underwent stimulus
dose titration to determine the convulsive threshold. Titration was a
ccomplished for each subject with both electrode placements during the
first and second ECT in a balanced design. Head measurements were mad
e prior to the first ECT. Results indicated that the convulsive thresh
old was higher for BL than RUL, higher for men than women, increased w
ith age, and increased with an increasing nasion-inion measurement in
women but not in men. We concluded that the convulsive threshold varie
s according to the choice of electrode placement, gender, and age as h
as been reported by others. We additionally report that the convulsive
threshold increases with increasing head size as reflected in the nas
ion-inion distance.