Today clinical toxicology and poisons control are widely lacking objec
tive criteria, e.g., analytical data, figures of kinetics and metaboli
sm in acute and chronic poisoning. Cooperation between clinical toxico
logy and an environmental specimen bank for human tissue will help to
overcome many difficulties and complement one another. The possible po
wer of such a co-operation is demonstrated by the example of the insti
tutions in Munster, Germany. The successful strategies used for settin
g-up an environmental specimen bank for human tissue may also be appli
ed in clinical toxicology and experimental toxicology. The frame of a
university medical clinic seems to be the ideal basis of an effective
co-operation of an Environmental Specimen Bank for Human Tissue, a Poi
sons Control Centre and clinical toxicology. In general a co-operation
of an environmental specimen bank for human tissue and a poisons cont
rol centre will be cost-saving and beneficial to both and an environme
ntal specimen bank for human tissue will gain the status of a unique t
ool for risk assessment of xenobiotics.