K. Abe et al., HEPATOCELLULAR-CARCINOMA ASSOCIATED WITH CHRONIC SCHISTOSOMA-MANSONI INFECTION IN A CHIMPANZEE, Journal of medical primatology, 22(4), 1993, pp. 237-239
Hepatocellular carcinoma associated with chronic Schistosoma mansoni i
nfection in a chimpanzee, estimated to be a 12-year-old and born in We
st Africa, is reported. The hepatic tumor appeared as a solitary firm
nodule, and histological examination revealed well-differentiated hepa
tocellular carcinoma with a trabecular pattern. Hepatitis B virus and
hepatitis C virus infections were excluded by serological testing in t
hat animal. This is the first report of hepatocellular carcinoma in th
e chimpanzee with schistosomiasis.