Deep venous thrombosis (DVT) of the upper extremity is a relatively un
common but important cause of morbidity, especially in young active pe
rsons. The causes of upper extremity DVT may be categorized as cathete
r-related, spontaneous (effort-related) and miscellaneous (e.g., traum
a, intravenous drug use). Diagnosis is based on clinical history and c
onfirmed by either duplex ultrasonography or contrast venography. Sign
ificant controversy surrounds the optimal management of upper extremit
y DVT Treatment options include conservative therapy, anticoagulation,
catheter-directed thrombolysis and surgical intervention to remove in
travascular clot or revise the anatomy of the costoclavicular space. E
arly aggressive treatment of active young patients may decrease long-t
erm morbidity.