Obesity is a common and serious health problem in the United States. E
xcess weight is associated with an increased mortality rate, as well a
s such risk factors as hypertension, hyperlipidemia and diabetes melli
tus. Numerous treatments are available for obesity. Behavioral therapy
, surgery and pharmacologic treatment have been used with varying degr
ees of success. Pharmacologic therapy includes primarily noradrenergic
agents and/or serotonergic agents. Newer preparations are currently u
nder development. Behavior modification, including regular exercise an
d the development of healthy eating habits, remains the best hope for
long-term weight loss. However, surgery or medication can be useful in
specific circumstances.