EFFECT OF TOXIN-544 AND TOXIN-514 FROM KARWINSKIA-HUMBOLDTIANA (BUCKTHORN) PLANT UPON FETAL DEVELOPMENT OF THE MOUSE

Authors
VALADEZALVIZO R RODRIGUEZALVARADO A DEVILLARREAL LM GONZALEZALANIS R PINEYROLOPEZ A
Citation
R. Valadezalvizo et al., EFFECT OF TOXIN-544 AND TOXIN-514 FROM KARWINSKIA-HUMBOLDTIANA (BUCKTHORN) PLANT UPON FETAL DEVELOPMENT OF THE MOUSE, Toxicon, 31(10), 1993, pp. 1329-1332
Citations number
12
Categorie Soggetti
Toxicology,"Pharmacology & Pharmacy
Journal title
Toxicon → ACNP
ISSN journal
00410101
Volume
31
Issue
10
Year of publication
1993
Pages
1329 - 1332
Database
ISI
SICI code
0041-0101(1993)31:10<1329:EOTATF>2.0.ZU;2-G
Abstract
The teratogenic effect of toxins 544 and 514 from K. humboldtiana upon the mouse embryo was evaluated. One half of the LD50 dose for the mou se was administered at day 8 of gestation. At the end of pregnancy, re production and fetal data were recorded. Dams treated with toxin 544, but not with toxin 514, showed a higher incidence of reabsorptions, ma lformations, as well as lower fetal length compared to the control gro up.