MODEL OF MAMMALIAN-CELL REPRODUCTIVE DEATH .1. BASIC ASSUMPTIONS AND GENERAL EQUATIONS

Authors
OBATUROV GM MOISEENKO VV FILIMONOV AS
Citation
Gm. Obaturov et al., MODEL OF MAMMALIAN-CELL REPRODUCTIVE DEATH .1. BASIC ASSUMPTIONS AND GENERAL EQUATIONS, Radiation and environmental biophysics, 32(4), 1993, pp. 285-294
Citations number
34
Categorie Soggetti
Biophysics,"Radiology,Nuclear Medicine & Medical Imaging","Environmental Sciences
Journal title
Radiation and environmental biophysics → ACNP
ISSN journal
0301634X
Volume
32
Issue
4
Year of publication
1993
Pages
285 - 294
Database
ISI
SICI code
0301-634X(1993)32:4<285:MOMRD.>2.0.ZU;2-L
Abstract
A systemic model describing the major radiobiological effects of vario us types of radiation is proposed. The model base lines were substanti ated, and general mathematical equations for cell survival developed. The model takes into consideration such physical and biological factor s as linear energy transfer, ion track structure, and structural and f unctional organization of interphase chromatin. This paper presents th e basic assumptions made and general equations for the cell killing.