PREVALENCE OF SORBITOL IN MULTIPLE-DOSE ACTIVATED-CHARCOAL REGIMENS IN EMERGENCY DEPARTMENTS

Study objectives: To determine the availability and use of premixed ac tivated charcoal in sorbitol preparations during multiple-dose activat ed charcoal therapy in the emergency department. Design and setting: A prospective telephone survey of all 911 receiving hospitals within th e catchment area of one poison center. Type of participants: Hospital pharmacy supervisors and ED charge nurses. Intervention: Hospital phar macy supervisors were surveyed about the available preparations of act ivated charcoal on their hospital's formulary, and ED charge nurses in these same hospitals were surveyed about the prevalence of sorbitol u se in multiple-dose activated charcoal regimens. Measurements and main results: Eleven hospitals (16%) stocked only activated charcoal in so rbitol preparations. Twenty-one hospitals (31%) had both activated cha rcoal in sorbitol preparations and activated charcoal without sorbitol preparations, and 35 hospitals (52%) had only activated charcoal with out sorbitol preparations. Repeat dosing of sorbitol during multiple-d ose activated charcoal therapy occurred in 33 of 67 (49%) of the EDs s urveyed. Conclusion: Sorbitol dosing is often repeated with activated charcoal during multiple-dose activated charcoal therapy in the ED bec ause of the ready availability (and sometimes exclusive availability) of premixed activated charcoal in sorbitol preparations.