VERSATILE ENZYMATIC DIACID ESTER SYNTHESIS OF BUTYL DELTA-D-GLUCOPYRANOSIDE

Authors
FABRE J BETBEDER D PAUL F MONSAN P PERIE J
Citation
J. Fabre et al., VERSATILE ENZYMATIC DIACID ESTER SYNTHESIS OF BUTYL DELTA-D-GLUCOPYRANOSIDE, Tetrahedron, 49(47), 1993, pp. 10877-10882
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
49
Issue
47
Year of publication
1993
Pages
10877 - 10882
Database
ISI
SICI code
0040-4020(1993)49:47<10877:VEDESO>2.0.ZU;2-N
Abstract
The enzymatic esterification of butyl alpha-D-glucopyranoside by diaci ds was investigated with pig pancreatic lipase in acetone. The nature of the acylating agent influenced the regiospecificity of the reaction . A chemoenzymatic reaction scheme was developed to obtain diacid este rs using an activated diacid as acyl donor, in a solvent-free process with the immobilized lipase of Mucor miehei (Lipozyme(R)).