When 73 heifers (60 of which were seronegative to pestivirus) were ins
eminated with pestivirus-contaminated semen from a transiently infecte
d bull, the conception rate to a single insemination was found to be n
ormal (65 per cent). Only three animals became systemically infected,
as determined by viraemia and seroconversion. Pestiviru was isolated f
rom the reproductive tracts of two of these heifers when they were sla
ughtered 42 or 43 days after insemination, Although the initial incide
nce of infection was low, a cycle of secondary transmission occurred a
pproximately 29 days after insemination, with a further eight heifers
(all seronegative) becoming infected from one group of 11 seronegative
and four seropositive animals.