CHEMISTRY AND CYCLIZATION REACTIONS OF PYRIMIDOTHIENOQUINOXALINE DERIVATIVES .4.

Authors
BADR MZA MAHGOUB SA ATTA FM MOUSTAFA OS
Citation
Mza. Badr et al., CHEMISTRY AND CYCLIZATION REACTIONS OF PYRIMIDOTHIENOQUINOXALINE DERIVATIVES .4., Journal of the Indian Chemical Society, 74(1), 1997, pp. 30-32
Citations number
4
Categorie Soggetti
Chemistry
Journal title
Journal of the Indian Chemical Society → ACNP
ISSN journal
00194522
Volume
74
Issue
1
Year of publication
1997
Pages
30 - 32
Database
ISI
SICI code
0019-4522(1997)74:1<30:CACROP>2.0.ZU;2-9
Abstract
The pyrimidothienoquinoxaline (2a; R = OH), derived from 1 and formami de, is thionated and chlorinated to 2b (R = SH) and 2f(R = Cl) respect ively. Treatment of 2f with hydrazine produces 2j (R = NHNH2), the lat ter giving 3a (R = SH) with carbon disulphide, 3c (R = CH(2)CO(2)Et) w ith diethyl malonate, and 4 with nitrous acid. Antibacterial and antif ungal activities of some of the products have been assessed.